IMPLEMENTATION

WP1-Development of 1d Data map

  • Development of data mining, text mining and 1D data mining services
  • Development of collaboration support services
  • Development of decision-making services. Dynamic update capabilities. A synergy of artificial and human intelligence

WP2-DEVELOPMENT OF A 3D MAP OF PROTEINS AND PROTEIN VARIANTS/PROTEOFORMS

  • Extraction of 3D structural information for proteins, protein variants/proteoforms as well as their interactions
  • Registration and segmentation of repurposed drugs, chemoinformatics. Collaboration and decision support services
  • Integration/analysis/interpretation of 3D structural information with 1D data. Collaboration and decision support services
  • Integration/analysis/interpretation of 1D (ADME-TOX genes, pharmacogenes) and construction of an optimized framework for predicting the 3D proteome (proteins, protein variants/proteoforms) and (drug) genome to ADME-TOX and pharmacogenomics
  • Dissemination of WP2 results

WP3- System/product evaluation

  • Application of the platform-product for the repurposing of sitagliptin
  • Evaluation of the platform-product for the repurposing of sitagliptin by computational approaches
  • Evaluation of the platform-product for the repurposing of sitagliptin with laboratory approaches
  • Dissemination of WP3 results

WP4- Technical feasibility study

  • Analysis of the current situation
  • Competitive and market analysis for the new innovative product
  • Risk assessment
  • SWOT analysis
  • Objectives and strategy (results enhancement) for the new product
  • Marketing strategy
  • Financial analysis (financial flows and sustainability)

WP5-INNOVATION FOR MEDIA

  • Writing the terms of use/provision for the service with the support of a specialized lawyer in matters of intellectual property protection