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WP1-Development of 1d Data map
- Development of data mining, text mining and 1D data mining services
- Development of collaboration support services
- Development of decision-making services. Dynamic update capabilities. A synergy of artificial and human intelligence
WP2-DEVELOPMENT OF A 3D MAP OF PROTEINS AND PROTEIN VARIANTS/PROTEOFORMS
- Extraction of 3D structural information for proteins, protein variants/proteoforms as well as their interactions
- Registration and segmentation of repurposed drugs, chemoinformatics. Collaboration and decision support services
- Integration/analysis/interpretation of 3D structural information with 1D data. Collaboration and decision support services
- Integration/analysis/interpretation of 1D (ADME-TOX genes, pharmacogenes) and construction of an optimized framework for predicting the 3D proteome (proteins, protein variants/proteoforms) and (drug) genome to ADME-TOX and pharmacogenomics
- Dissemination of WP2 results
WP3- System/product evaluation
- Application of the platform-product for the repurposing of sitagliptin
- Evaluation of the platform-product for the repurposing of sitagliptin by computational approaches
- Evaluation of the platform-product for the repurposing of sitagliptin with laboratory approaches
- Dissemination of WP3 results
WP4- Technical feasibility study
- Analysis of the current situation
- Competitive and market analysis for the new innovative product
- Risk assessment
- SWOT analysis
- Objectives and strategy (results enhancement) for the new product
- Marketing strategy
- Financial analysis (financial flows and sustainability)
WP5-INNOVATION FOR MEDIA
- Writing the terms of use/provision for the service with the support of a specialized lawyer in matters of intellectual property protection